Do you skip meals and then overload your system with one ginormous meal?  Your body can only digest so much at one time.  In addition, you will slow down your metabolism.  Your body will think it is starving and store the food at the next meal. 

I never recommend eating less than three to five times a day (small portions that include complex carbs and low fat proteins). Do not let four hours pass without eating. This you will not starve and then binge at your next meal.

Not everyone has the same metabolism.  In the long term, one meal a day will do more damage than good to your body. Your body will burn muscle tissue before it will burn fat. This will destroy your metabolism in the long term.  Everyone has a unique metabolism, there are no cookie cutter solutions. For most people, though, if you have a normal or slightly fast metabolism, you body will be "waiting" for more food 3-5 hours after the single meal.

Fuel your body and your mind every 3 - 5 hours.
How many meals do you eat every day?